In 19th-century New Mexico, a father (Tommy Lee Jones) comes back home, hoping to reconcile with his adult daughter Maggie (Cate Blanchett). Maggie’s daughter is kidnapped, forcing father and estranged daughter to work together to get her back.

Hondo Lane, a despatch rider for the cavalry, encounters Angie Lowe, a woman living alone with her young son in the midst of hostile Apache territory. She presumes she is safe because the Apaches, under their chief Vittorio, have always left them alone. Later Lane has a run-in with Angie’s reprobate husband and is forced to kill him, not knowing who he is. Vittorio captures Lane and to save his life, Angie tells the Apache chief that Lane is her husband, unaware that Lane has killed her real husband. In order to protect her from a forced marriage with one of the Apache, Lane reluctantly goes along with the lie, though he knows the truth must eventually come out, to Vittorio and to Angie, both.

An Apache warrior who defies U.S. attempts to bring the Indians under control grapples with an array of U.S. soldiers sent to subdue his revolt. Sympathetic scouts seek to bring Geronimo back to the reservation before he is hunted down.