Having always wanted to be a disc-jockey, Howard Stern works his way painfully from radio at his 1970’s college to a Detroit station. It is with a move to Washington that he hits on an outrageous off-the-wall style that catches audience attention. Despite his on-air blue talk, at home he is a loving husband. He needs all the support he can get when he joins NBC in New York and comes up against a very different vision of radio.

Jesse and Chester, two bumbling stoners, wake up one morning from a night of partying and cannot remember where they parked their car which prompts them on a journey to find it and along the way, they encounter a variety of people who include their angry girlfriends Wilma and Wanda whose house they trashed, an angry street gang, a transexual stripper hounding them for a suitcase full of stolen money, a cult of alien seeking fanatics, and a group of aliens in human form looking for a mystical device that could save or destroy the world.