Harvard Medical School graduate Dr. Ted Grey arrives at one of the nations most prestigious Pathology programs and is quickly noticed by the program’s privileged and elite band of pathology interns who invite him into their crowd. It is also here, where he is introduced to Dr. Jake Gallo, who brings him to a secluded wing, where he and four other indulge in there after-hours, extra-curricular activities…finding ways to commit the perfect murder!

Once a promising writer, John Hayson now gets by on the odd writing job. A personal tragedy has left him dispassionate about the world and his work and he lives his life in limbo. In the midst of this existential crisis he attends a high school reunion and meets three old friends; acquaintances he’s tried to forget but who now emerge like ominous shadows from his past. Once again, face to face with the love of his life, Hayson tries to right old wrongs and get his life back on track. However, life has other plans, and he realizes that the past is best laid to rest or it might haunt you forever. He soon finds himself embroiled in a nightmarish brew of deceit, passion and murder. Wanted by the police for a heinous killing, he must choose between succumbing to his darkest desires or the light that will renew his faith in himself and his future.

The psychiatric intern Clark Stevens (Joshua Leonanrd) comes to Cunningham Hall, a mental healthy facility administrated by Dr. Franks (Lance Henriksen), for a training period before his graduation in medical college. He gets close to the resident Sara (Jordan Ladd) and to Ben London, a dangerous patient lodged in cell 44 in the basement of the clinic. Clark becomes intrigued with a boy, who seems to be a ghost, and finds that Dr. Franks does not use real medication in the patients. A further investigation shows hidden dark secrets in the clinic.

When a boy starts having a premonition of Flight 180 crashing, he tells his friends before they board that it is a bad idea and to not to take the flight. His friends listen to him and don’t go and soon after the plane crashes. Now since his friends didn’t get on the plane one by one they are getting killed in mysterious ways.