Retired FBI agent Will Graham (William L. Petersen) returns to action to hunt down a serial killer by using his ability to get inside the psychopath’s mind. However, it was this ability that drove him into retirement in the first place. The process of tracking and capturing the infamous Hannibal Lecter (Brian Cox) took a tremendous psychic toll on Graham, causing him to spent time in a mental hospital. With another madman on the loose, Graham has no choice but to return to duty, though he knows that it might cost him his family and his sanity.

To get the old mind-set back, Graham visits Hannibal Lecter in his high-security jail cell. However, the manipulative Lecter plays both sides and warns the new killer that Graham is on his trail, telling him to destroy Graham’s family to protect himself. In order to save his own family, Graham must risk everything to once again enter into the mind of the criminally insane.

With MANHUNTER, Mann raises the bar for serial killer films, imbuing his killer with an almost sympathetic quality while keeping him extremely menacing and clearly dangerous. Based on the Thomas Harris novel RED DRAGON, which serves as the prequel to THE SILENCE OF THE LAMBS, MANHUNTER is a masterpiece of gripping storytelling and psychological horror.

Part four in the Hannibal Lecter Quadrilogy. Having escaped the asylum in “Silence of the Lambs,” Dr Lecter goes into hiding in Florence, Italy. Back in America, Mason Verger, an old victim of the doctor’s, seeks revenge. Disfigured and confined to a life-support system, he plans to draw Lecter out of his hiding place, using the one thing he truly cares for: Clarice Starling.

FBI Agent Will Graham has been called out of early retirement to catch a serial killer, known by authorities as “The Tooth Fairy”. He asks for the help of his arch-nemesis, Dr. Hannibal “The Cannibal” Lecter, so that he can be able to catch “The Tooth Fairy” and bring him to justice. The only problem is that “The Tooth Fairy” is getting inside information about Graham and his family from none other than Dr. Lecter.

Young FBI agent Clarice Starling is assigned to help find a missing woman to save her from a psychopathic serial killer who skins his victims. Clarice attempts to gain a better insight into the twisted mind of the killer by talking to another psychopath Hannibal Lecter, who used to be a respected psychiatrist. FBI agent Jack Crawford believes that Lecter who is also a very powerful and clever mind manipulator have the answers to their questions to help locate the killer. Clarice must first try and gain Lecter’s confidence before he is to give away any information.