Joan Wilder is a mousey writer of romance novels. She finds a package from her sister mailed from Colombia in her mailbox. A call from her sister tells her that she has been kidnapped and that bringing the package to Colombia is necessary for her safety and release. Being fairly clueless, she leaves for Colombia to rescue her sister. She is lost within hours of her arrival. She is nearly murdered by one of the men searching for the package when Jack Colton, a fairly low life American rescues her. They begin a journey through the jungle with bullets flying nearby. Is Joan up to all of this? What a way to find out.

After the continuous sleep walking episodes of Sharon, the young daughter of Rose Da Silva, the decision is made to take Sharon to the place only mentioned in her restless dreams- Silent Hill. However, the road to Silent Hill is anything but easy to access, and Rose creates a high speed chase between herself and a police officer only to end in a crash for them both. When she wakes up, Sharon has disappeared and Rose is at the entrance to the deserted, dream-like town of Silent Hill. As Rose begins the search for her daughter, she does not realize the terror and mystery surrounding her. Rose is led on a blind search for her beloved daughter, finding herself getting more and more entwined into disturbing past of Silent Hill.

When detective Eric Matthews (Donnie Wahlberg) is called to a crime scene of a victim of Jigsaw (Tobin Bell), he finds a lead to the place where he is hidden. Once there, he realizes that Jigsaw trapped his son Daniel Matthews (Erik Knudsen) with three women and four men in a shelter, and they are inhaling a lethal nerve gas. If they do not use an antidote within two hours, they will die. Eric follows with increasing desperation the death of each member of the group in monitors, while trying to convince Jigsaw to release his son.