In this modern retelling of a classic urban legend, a mother finds herself at odds with a unremitting flight crew and her own sanity when her daughter vanishes in the middle of a flight, with only a few clues left behind. She must now challenge the boundaries of her will and her mind in her desperate search.

Big Bird is the central character in this film. A social worker, upon seeing that Big Bird doesn’t live with other birds, sets him up with a Dodo family to be adopted. Unfortunately he is not happy in his new surroundings and, trying to get back to Sesame Street, runs away from home. On the way, he encounters adventure with all kinds of people, and discovers where he really wants to be: His true home - Sesame Street.

A grieving mother, Telly Paretta, is struggling to cope with the loss of her 9-year-old son. She is stunned when her psychiatrist and her husband tell her that she has created eight years of memories of a son she never had. But when she meets the father of one of her son’s friend who is having the same experience, Telly embarks on a mission to prove her son’s existence and her sanity.

After their young son, Adam (Bright), is killed in an accident, a couple (Kinnear, Romijn-Stamos) approach an expert (De Niro) in stem cell research about bringing him back to life through an experimental and illegal cloning and regeneration process. When Adam comes back to them, however, he’s.. different…