New York City. Melvin Udall, a cranky, bigoted, obsessive-compulsive writer, finds his life turned upside down when neighboring gay artist Simon is hospitalized and his dog is entrusted to Melvin. In addition, Carol, the only waitress who will tolerate him, must leave work to care for her sick son, making it impossible for Melvin to eat breakfast.

The script begins as a young Hughes directs one of Scorsese’s favorite films, Hell’s Angels. Hughes was so obsessed with perfection in the aerial sequences that he waits forever for perfect conditions, right down to cloud formations. The Aviator ends in 1946, when Hughes was still a dashing young man and romancing actresses like Ava Gardner and Katharine Hepburn.

Harvey Pekar is file clerk at the local VA hospital. His interactions with his co-workers offer some relief from the monotony, and their discussions encompass everything from music to the decline of American culture to new flavors of jellybeans and life itself. At home, Harvey fills his days with reading, writing and listening to jazz. His apartment is filled with thousands of books and LPs, and he regularly scours Cleveland’s thrift stores and garage sales for more, savoring the rare joy of a 25-cent find. It is at one of these junk sales that Harvey meets Robert Crumb, a greeting card artist and music enthusiast. When, years later, Crumb finds international success for his underground comics, the idea that comic books can be a valid art form for adults inspires Harvey to write his own brand of comic book. An admirer of naturalist writers like Theodore Dreiser, Harvey makes his American Splendor a truthful, unsentimental record of his working-class life, a warts-and-all self portrait. First published in 1976, the comic earns Harvey cult fame throughout the 1980s and eventually leads him to the sardonic Joyce Barber, a partner in a Delaware comic book store who end ups being Harvey’s true soul mate as they experience the bizarre byproducts of Harvey’s cult celebrity stature.

Barr is a psychiatrist who falls in love with the sister of one of his clients. She’s beautiful and married (to a gangster). She hates her husband but is unable to escape from him. To avoid spoilers, someone dies, but who did what and why ?