Harvard Medical School graduate Dr. Ted Grey arrives at one of the nations most prestigious Pathology programs and is quickly noticed by the program’s privileged and elite band of pathology interns who invite him into their crowd. It is also here, where he is introduced to Dr. Jake Gallo, who brings him to a secluded wing, where he and four other indulge in there after-hours, extra-curricular activities…finding ways to commit the perfect murder!

Lee Holloway is a smart, quirky woman in her twenties who returns to her hometown in Florida after a brief stay in a mental hospital. In search of relief from herself and her oppressive childhood environment, she starts to date a nerdy friend from high school and takes a job as a secretary in a local law firm, soon developing an obsessive crush on her older boss, Mr. Grey. Through their increasingly bizarre relationship, Lee follows her deepest longings to the heights of masochism and finally to a place of self-affirmation.

Since a road accident left him with serious facial and bodily scarring, a former ‘TV scientist’ has become obsessed by the marriage of motor car technology with what he sees as the ‘raw sexuality’ of car-crash victims. The scientist, along with a crash victim he has recently befriended, sets about performing a series of sexual acts in a variety of motor vehicles, either with other crash victims or with prostitutes who they contort into the shape of trapped-corpses. Ultimately, the scientist craves a suicidal union of blood, semen and engine coolant, a union with which he becomes dangerously obsessed.