Harvard Medical School graduate Dr. Ted Grey arrives at one of the nations most prestigious Pathology programs and is quickly noticed by the program’s privileged and elite band of pathology interns who invite him into their crowd. It is also here, where he is introduced to Dr. Jake Gallo, who brings him to a secluded wing, where he and four other indulge in there after-hours, extra-curricular activities…finding ways to commit the perfect murder!

His world in complete disorder after his break-up with a famous actress, Carter, a young soft-core porn writer, goes to suburban Detroit to care for his sickly Grandmother and heal his broken heart. Along the way he forms a special bond with the family that lives across from his Grandma, and changes the life of each woman. In the course of this, as is required in every film—and thus the world, he changes his own life as well.

Joe Young is a young Mormon actor who preaches the word of God in LA and can’t get anything from it. One day he stumbles on the set of new porno movie shot by well known porn director Maxxx Orbison. Maxxx chooses Joe for the title part in his new movie Captain Orgazmo. Joe soon befriends short and skinny Ben Chapleski (his sidekick in the film), who invented a ray-gun which emits a light beam that causes the most intense orgasm in whoever it hits (called Orgasmorator). Unexpectedly movie Captain Orgazmo becomes a cult hit, and Joe’s girlfriend Lisa accidentally sees the movie in the video store - and the problems begin.

An aging antique dealer, Jesus Gris, happens upon an elegant mechanized scarab. When opened, it painfully stabs whomever is holding it, but the wound brings youthful vigor and a vampire’s need for blood. The device is relentlessly pursued by a dying tycoon, Dieter de la Guardia, whose nephew Angel, reluctant to see his uncle live a moment longer, must still do the old man’s bidding. Meanwhile, Gris’s desires endanger his own granddaughter, Aurora.

Eddie Hawkins, called Hudson Hawk has just been released from ten years of prison and is planning to spend the rest of his life honestly. But then the crazy Mayflower couple blackmail him to steal some of the works of Leonardo da Vinci. If he refuses, they threaten to kill his friend Tommy.