Top London cop, PC Nicholas Angel (Pegg) is good. Too good. And to stop the rest of his team looking bad, he is reassigned to the quiet town of Sandford. He is paired with Danny Butterman (Frost), who countlessly questions him on the action lifestyle. Everything seems quiet for Angel, until two actors are found decapitated. It is address to as an accident, but Angel isn’t going to accept that, especially when more and more people turn up dead. Angel and Danny clash with everyone, whilst trying to uncover the truth behind the mystery of the apparent “acidents”.

Elizabeth Masterson (Reese Witherspoon), a dedicated Doctor in San Francisco, had almost no time for anything. When her sister with two kids set her up on a date, she gets into a tragic car crash and gets in a coma. Meanwhile, an artist named David Abbott (Mark Ruffalo) moves into San Francisco and coincidentally, into Elizabeth’s apartment for rent. While at the apartment, Elizabeth’s spirit haunts him. She doesn’t remember who she is, who her family is, and what she did - All that she remembered was her apartment and where everything was. To settle the arguments, Dacid agrees to figure out who Elizabeth really is. When they get close to figuring out who she is, they eventually find love in each other and as they finally know who she really is, they learn that fate really has put them both together.

The architect Michael Newman has a typical middle-class family with his lovely and gorgeous wife Donna and their son Ben and daughter Samantha, and a constant visit of his parents. However, Michael is workaholic and under stress, trying to satisfy his boss with overwork and get a partnership in his company, giving priority to his work and neglecting the family issues. When the tired Michael goes to a department store to buy an universal remote control, he rests on a bed and he meets the weird salesman Morty that offers him a remote control capable of controlling his own universe. Michael uses too much and loses the control of the device, having his own life controlled by the remote control. Then Michael sees the worthwhile parts of his personal life he missed while working, and in the end of his life he lately concludes that the family comes first.

Nelson (Keanu Reeves) is a man devoted to his advertising career in San Francisco. One day, while taking a driving test at the DMV, he meets Sara (Charlize Theron). She is very different from the other women in his life. Nelson causes her to miss out on taking the test and later that day she tracks him down. One thing leads to another and Nelson ends up living with her through a November that will change his life forever.